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Shu-Chuan Yang,Ph.D.

SHU-CHUAN YANG 

Associate Professor

 

ACADEMIC TRAINING

National Yang-Ming University                                                  Taipei, Taiwan

PH.D., Institute of Physiology, National Yang-Ming (1999-2004)

M.S., Institute of Physiology, National Yang-Ming (1997-1999)

RESEARCH INSTEREST

1.     The mechanisms of CART peptide psychostimulant-like effect. (2004~2008)

(1)   Effects of cocaine- and amphetamine-regulated transcript peptide on regulation of midbrain dopaminergic systems (NSC94-2320-B-277-001, 2005/08/01-2006/07/31)

(2)   Effects and mechanisms of gonadal hormones on the actions of cocaine- and amphetamine-regulated (CART) peptide to midbrain dopaminergic systems, and the interactions of CART peptide with opioidergic and GABAergic systems (NSC95-2320-B-277-001-MY2, 2006/08/01-2008/07/31)

2.     The mechanisms of CART peptid involve neuronal protection. (2008~2011)

(1)  The role of CART peptide in gonadal hormones-mediated neuroprotection (NSC97-2314-B-277-001-MY3, 2008/08/01-2011/07/31)

3.     Roles of BDNF and PGC-1 alpha in the mouse model of ADHD (MOST 103-2410-H-277-001 2014/08/01-2015/07/31)

4.     The mechanisms of radiation-induced cognitive impairment

HONOR

7th International Brain Research Organization (IBRO) World Congress of Neuroscience travel award (2007)

第89回日本生理學大會優選論文獎 (2012)  89th Annual Meeting of the Physiological Society of Japan

PUBLICATION

1.     Shu-ChuanYang co, Chien-Lin Chen co, Chih-HsunYi , Tso-Tsai Liu, *Kun-Ruey Shieh: Changes in Gene Expression Patterns of Circadian-Clock, Transient Receptor Potential Vanilloid-1 and Nerve Growth Factor in Inflamed Human Esophagus. Sci Rep. 2015 Sep 4;5:13602. (co These Authors contributed equally to this work)(2014 IF: 5.578, MULTIDISCIPLINARY SCIENCES: 5/57=8.7%)

2.     co Tseng HLco Yang SCYang SH, *Shieh KR: Hepatic circadian-clock system altered by insulin resistance, diabetes and insulin sensitizer in mice. PLoS One. 2015 Mar 23;10(3):e0120380. (Tseng HL and Yang SC contributed equally to this work as the co-first author)(2013 IF: 3.534, MULTIDISCIPLINARY SCIENCES: 8/55=14.5%)

3.     KR. Shieh, SC. Yang, HL. Tseng, CH. Yi, TT. Liu and *CL. Chen: Evidence for Up-Regulation of Purinergic Receptor Genes Associating with TRPV1 Receptors and Neurotrophic Factors in the Inflamed Human Esophagus. Current Molecular Medicine 2014, 14: 1-10 (2013 IF:3.612, MEDICINE, RESEARCH & EXPERIMENTAL:31/124=25%)

4.     Yang SC, Tseng HL, *Shieh KR: Circadian-clock system in mouse liver affected by the insulin resistance. Chronobiology International. 2013, 30: 796–810 (2013 IF: 2.487, BIOLOGY: 19/85=22.3%)

5.     co Hsieh MC, co Yang SC, Tseng HL, Hwang LL, Chen CT, *Shieh KR: Abnormal expressions of circadian-clock and circadian clock-controlled genes in the livers and kidneys of long term, high-fat diet-treated mice. International Journal of Obesity. 2010, Feb;34(2):227-39.  (Hsieh MC and Yang SC contributed equally to this work as the co-first author) (2013 IF: 5.386, NUTRITION & DIETETICS: 6/79 = 7.5%)

6.     Shieh KR, *Yang SC: Effects of estradiol on the stimulation of dopamine turnover in mesolimbic and nigrostriatal systems by cocaine- and amphetamine-regulated transcript peptide in female rats. Neuroscience. 2008, 154:1589-1597. (2011 IF: 3.380, NEUROSCIENCES: 94/244 = 38.5%)

7.     Shieh KR, Lee HJ, *Yang SC: Different patterns of food consumption and locomotor activity between Taiwanese native rodent, formosan wood mouse (Apodemus semotus), and common laboratory mouse, C57BL/6 (Mus musculus). Chinese Journal of Physiology. 2008, 51: 129-135. (2013 IF: 1.275, PHYSIOLOGY: 65/81 = 80.2%)

8.     Yang SC, *Shieh KR: Gonadal Hormones-mediated Effects on the Stimulation of Dopamine Turnover Mesolimbic and Nigrostriatal Systems by Cocaine- and Amphetamine-regulated Transcript (CART) Peptide in Male Rats. Neuropharmacology. 2007, 53: 801-809. (2013 IF: 4.819, PHARMACOLOGY & PHARMACY: 23/256 = 8.9%)

9.     Yang SC, Shieh KR, *Li HY: Cocaine- and amphetamine-regulated transcript (CART) peptide in the nucleus accumbens participates in the regulation of feeding behavior in rats. Neuroscience. 2005, 133: 841-851. (2013 IF: 3.327, NEUROSCIENCES: 104/252 = 41.2%)

10.  Yang SC, *Shieh KR: Differential effects of melanin concentrating hormone on the central dopaminergic neurons induced by the cocaine- and amphetamine-regulated transcript. Journal of Neurochemistry. 2005, 92: 637-646. (2013 IF:4.244, NEUROSCIENCES: 63/252 = 25%)

11.  *Shieh KR, Yang SC, Lu XY, Akil H, Watson SJ: Diurnal rhythmic expression of the rhythm-related genes, rPeriod1, rPeriod2, and rClock, in the rat brain. Journal of Biomedical Science. 2005, 12: 209-217. (2013 IF: 2.736, MEDICINE, RESEARCH & EXPERIMENTAL:49/124 = 39.5%)

12.  Yang SC, *Shieh KR: Effects of the cocaine- and amphetamine-regulated transcript peptide on the turnover of tuberoinfundibular dopaminergic neurons and serum prolactin levels: studies using estrogen, melanin concentrating hormone, and melanocortin. Neuropharmacology. 2004, 47: 1070-1080. (2013 IF: 4.819, PHARMACOLOGY & PHARMACY: 23/256 = 8.9%)

13.  Yang SC, Pan JT and *Li HY: CART peptide increases the mesolimbic dopaminergic neuronal activity: a microdialysis study. European Journal of Pharmacology 2004, 494: 179-182. (2013 IF:2.684, PHARMACOLOGY & PHARMACY: 98/256 = 38.2%)

14.  Yang SC and *Pan JT: Differential effects of colchicine on central dopaminergic neuronal activity and prolactin secretion in estrogen-primed ovariectomized rats. Chinese Journal of Physiology. 2003, 46:15-18. (2013 IF: 1.275, PHYSIOLOGY: 65/81 = 80.2%)

15.  Yuan ZF, Yang SC and *Pan JT: Effects of prolactin-releasing peptide on tuberoinfundibular dopaminergic neuronal activity and prolactin secretion in estrogen-treated female rats. Journal of Biomedical Science. 2002, 9:112-118. (2013 IF: 2.736, MEDICINE, RESEARCH & EXPERIMENTAL:49/124 = 39.5%)